Regenerative Treatments

Salmon DNA (Polynucleotide) — Face

Using purified DNA fragments to signal the skin's own repair and regeneration processes.

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Regenerative Treatments at LIN Europe Clinic, Istanbul

This treatment involves injecting purified polynucleotide chains into the skin's deeper layer. These molecules act as signals, encouraging the cells responsible for skin structure—the fibroblasts—to produce more collagen and elastin. The aim is to improve the skin's density and its ability to hold moisture. The response is governed by the skin's existing condition: its thickness, the accumulated effect of sun exposure over years, and its underlying cellular health.

A polynucleotide treatment is not planned against a photograph or an ideal shape. Its purpose is to improve the fabric of the skin itself, not to alter facial contours. Therefore, the approach is different for each person, tailored to the specific concerns observed on their skin—be it fine lines around the eyes, a loss of elasticity in the cheeks, or textural changes. The treatment plan is built on an assessment of skin quality, not on changing the underlying anatomy.

Medical Aesthetics at this clinic

Results

These are medical aesthetics cases performed here, not all of them this operation — some include an uplift, which is a different procedure. Every pair is on the results page with its own description.

Lip Filler — Before
Before
Lip Filler — After
After

Lip Filler

A fuller smile, still your own

A measured lip filler result, judged against the rest of the face rather than a trend.

The treatment addresses the skin as an organ, aiming to improve its fundamental health. This is not a substitute for procedures that lift tissue or restore lost volume. Instead, it works on the quality of the skin that covers these structures. A healthier, more resilient skin provides a better foundation, whether as a standalone improvement or in concert with other treatments. The process is biological; it prompts the body to repair itself, and the changes appear gradually as the skin rebuilds from within.

No price list. Every plan is quoted for one person and one anatomy, so a figure only means something once someone has looked at yours — you get one in writing before you commit to anything.

This article is general information, not medical advice, and does not replace a consultation. Every procedure carries risk and outcomes vary from person to person.

Guests of the clinic, on camera

Guest Films

Filmed and published with our guests’ consent. Each speaks only for their own treatment — every face heals differently, and these are individual outcomes, not a promise of yours.

Questions people ask

Answered as far as they can be answered in writing. Anything that depends on your own anatomy is answered by a surgeon looking at it.

Is salmon DNA a filler or is it like Botox?

Polynucleotide treatment is neither. Fillers add volume using substances like hyaluronic acid. Neurotoxins relax muscles to soften lines. This treatment works differently, using purified DNA fragments to signal your own skin cells—the fibroblasts—to produce more collagen and elastin. The aim is to improve the skin's own density, texture, and hydration, not to fill a space or block a nerve signal.

How many sessions of salmon DNA are needed?

A treatment plan is not a fixed number of sessions. It is designed after an in-person assessment of your skin's condition. The factors that influence the plan include the skin's thickness, its history of sun exposure, its natural elasticity, and the specific concerns being addressed. The approach is to stimulate a biological response, and the number of treatments is determined by how the skin is expected to react.

Where does the DNA in the treatment come from?

The polynucleotides are derived from salmon germ cells, as this source DNA is very similar to human DNA. The material is highly purified and processed in a laboratory to be sterile and biocompatible, removing other proteins that could cause reactions. Its purpose is to act as a biological signal for cellular repair. The consultation includes a review of any allergies, particularly to fish products.

Does salmon DNA treatment hurt?

The treatment involves a series of small injections made with a fine needle into the skin. A topical anaesthetic cream is typically applied to the skin surface beforehand to numb the area and improve comfort during the procedure. Sensation varies from person to person and by the area being treated. The focus is on making the administration of the treatment as manageable as possible.

What should I bring to my salmon DNA consultation?

It is helpful to have a list of your current skincare products. Be prepared to discuss any previous cosmetic treatments, including injectables, peels, or laser therapy, and when they were performed. Information about your general health, any known allergies (especially to fish or seafood), and your typical sun exposure habits will also be important for building an accurate assessment of your skin.

Where is the salmon DNA treatment performed?

All injectable treatments are carried out in a clinical setting within an accredited hospital in Istanbul. The specific hospital is confirmed in your written treatment plan before any travel is arranged. The procedure is performed by a qualified medical practitioner. If required, an interpreter is present throughout your appointment to ensure clear communication between you and the clinical team.

Guest Stories

Told quietly, by those who lived it.

  • ★★★★★
    Their attention to detail is exceptional! They truly listen to your goals and carefully craft a personalized plan without ever making you feel rushed.
    DustinRead on Trustindex
  • ★★★★★
    I had my hair transplant at Lin Europe Clinic, and my experience was excellent from start to finish. Everything was well organized, the procedure was smooth, and I didn't feel any pain during the treatment. The entire team was professional, friendly, and very caring. I really appreciated their attention to detail and the level of care they provided.
    Akib RahmanRead on Google
  • ★★★★★
    I had the Baby Face Laser treatment at Lin Europe Clinic, and I had a great experience. The team was very professional, friendly, and made me feel comfortable throughout the entire process. They explained everything clearly and took the time to answer all of my questions. The clinic was clean, well-organized, and the treatment was carried out with great care.
    Tina KandeaRead on Google

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Marina Clinic · Bakırköy
Zeytinlik, Kennedy Cad. No: 24, İç Kapı No: 1, 34140 Bakırköy / İstanbul